US Patent Issued to Citryll on March 31 for "Antibodies binding to citrullinated histone 2A and/or 4" (Dutch Inventors)

ALEXANDRIA, Va., March 31 -- United States Patent no. 12,590,143, issued on March 31, was assigned to Citryll B.V. (Oss, Netherlands).

"Antibodies binding to citrullinated histone 2A and/or 4" was invented by Jozef Maria Hendrik Raats (Nijmegen, Netherlands), Renato Gerardus Silvano Chirivi (Oosterhout, Netherlands) and Johannes Wilhelmus Gerardus Van Rosmalen (Oss, Netherlands).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides antibodies or binding fragments thereof directed against citrulline-containing epitopes. The antibodies or binding fragments thereof of the invention can be used in therapy, for example in the treatment or prevention of Neutrophil Extracellular Trap (NET)-associated...