US Patent Issued to CHUGAI SEIYAKU on May 26 for "Method for producing peptide containing non-natural amino acid" (Japanese Inventors)

ALEXANDRIA, Va., May 26 -- United States Patent no. 12,637,494, issued on May 26, was assigned to CHUGAI SEIYAKU K.K. (Tokyo).

"Method for producing peptide containing non-natural amino acid" was invented by Sakiko Yoshii (Kamakura, Japan), Koichiro Shimomura (Kamakura, Japan) and Sou Ishino (Kamakura, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention revealed that translating an mRNA that encodes a peptide containing an unnatural amino acid in a translation system that contains a ribosome containing an engineered L31 protein can increase the amount of the translated peptide. Furthermore, the invention revealed that by using this ribosome, the relative amount of by-products can also ...