ALEXANDRIA, Va., July 7 -- United States Patent no. 12,674,177, issued on July 7, was assigned to Christian Kupatt (Munich).
"AAV vectors for vascular gene therapy in coronary heart disease and peripheral ischemia" was invented by Christian Kupatt (Munich) and Rabea Hinkel (Munich).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to the provision of a gene therapy for coronary heart disease and peripheral ischemia in mammals. One embodiment is an adeno-associated viral vector (AAV vector) comprising a first gene encoding a myocardin-related transcription factor A (MRTF-A). The invention further also relates to a pharmaceutical composition comprising an AAV vector of the invention and a pha...