US Patent Issued to Chiome Bioscience on July 14 for "Method for promoting diversification of antibody variable region" (Japanese Inventors)

ALEXANDRIA, Va., July 14 -- United States Patent no. 12,680,195, issued on July 14, was assigned to Chiome Bioscience Inc. (Tokyo).

"Method for promoting diversification of antibody variable region" was invented by Keisuke Niikura (Tokyo) and Yosuke Kamimura (Tokyo).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method for promoting diversification of variable regions of an antibody, particularly a method for promoting diversification of the amino acid sequences of variable regions of an antibody generated by an avian B cell population, the method including suppressing the PI3KAlpha activity of each avian B cell comprised in the avian B cell population expressing the antibody."

The patent was filed on Jan....