ALEXANDRIA, Va., July 7 -- United States Patent no. 12,674,141, issued on July 7, was assigned to CHINA MEDICAL UNIVERSITY (Taichung, Taiwan).
"Gene-engineered mesenchymal stem cells and applications thereof" was invented by Woei-Cherng Shyu (Taichung, Taiwan), Chien-Lin Chen (Taichung, Taiwan), Yi-Hui Lee (Taichung, Taiwan), Long-Bin Jeng (Taichung, Taiwan) and Chang-Hai Tsai (Taichung, Taiwan).
According to the abstract* released by the U.S. Patent & Trademark Office: "Accordingly, the present disclosure provides a population of genetically engineered mesenchymal stem cells (MSCs), comprising an expression vector comprising an Akt or HGF gene and a PD-L1 gene. Also provided is a method for synergistically increasing survival status and ...