ALEXANDRIA, Va., Aug. 25 -- United States Patent no. 12,714,733, issued on Aug. 25, was assigned to CHILDREN'S HOSPITAL OF EASTERN ONTARIO RESEARCH INSTITUTE INC. (Ottawa) and Iovance Biotherapeutics Inc. (San Carlos, Calif.).
"Sequential heterologous boost oncolytic viral immunotherapy" was invented by David Stojdl (Ottawa), Justyna Kmiecik (Ottawa) and Michael F. Burgess (Chester, N.J.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to a sequential boost oncolytic viral immunotherapy and compositions for use in the same. More particularly, the disclosure relates to oncolytic viruses that significantly increase antigen-specific T cell-mediated immune responses when combined in ...