US Patent Issued to Children's Hospital Medical Center, UNIVERSITY OF CINCINNATI on Aug. 18 for "Combination therapy for VAV3 cancer" (Ohio Inventors)

ALEXANDRIA, Va., Aug. 18 -- United States Patent no. 12,708,627, issued on Aug. 18, was assigned to Children's Hospital Medical Center (Cincinnati) and UNIVERSITY OF CINCINNATI (Cincinnati).

"Combination therapy for VAV3 cancer" was invented by Nicolas Nassar (Cincinnati) and Jose A. Cancelas (Cincinnati).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are compositions and methods for treating an individual having a leukemia. In certain aspects, the methods may include administering an IODVA1 compound and ponatinib to an individual in need thereof for treatment of a leukemia, which may include, for example, TKI-resistant leukemia, TKI-resistant Ph+ B-ALL, Chronic Myelogenous Leukemia (CML), Ph...