ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,747,231, issued on Sept. 29, was assigned to CHIESI FARMACEUTICI S.p.A. (Parma, Italy).

"(AZA)quinoline 4-amines derivatives as P2X 3 inhibitors" was invented by Claudio Fiorelli (Parma, Italy), Paolo Bruno (Parma, Italy), Matteo Biagetti (Parma, Italy), Charles Baker-Glenn (Parma, Italy) and Herve Van De Poel (Parma, Italy).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to compounds of formula (I) inhibiting P2X purinoceptor 3; particularly the invention relates to compounds that are (aza)quinoline 4-amines derivatives, methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use the...