ALEXANDRIA, Va., June 2 -- United States Patent no. 12,643,897, issued on June 2, was assigned to CHIA TAI TIANQING PHARMACEUTICAL GROUP Co. LTD. (Lianyungang, China).

"Fused tri-cyclic compound as a PDE3/PDE4 dual inhibitor" was invented by Yunfu Luo (Shanghai), Jianfeng Pan (Shanghai), Guoli Zhang (Shanghai), Sheng Su (Shanghai), Yong Wang (Shanghai) and Shuhui Chen (Shanghai).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided is a fused tri-cyclic compound as PDE3/PDE4 dual inhibitor, and a use thereof in the preparation of drugs for PDE3/PDE4 associated diseases, particularly in medicinal functions such as chronic obstructive pulmonary disease (COPD). Provided are specifically a compound of formula (...