US Patent Issued to CHAKRABARTI ADVANCED TECHNOLOGY on March 3 for "Methods for the design of nonallosteric sirtuin activating compounds" (New Jersey Inventors)

ALEXANDRIA, Va., March 3 -- United States Patent no. 12,565,673, issued on March 3, was assigned to CHAKRABARTI ADVANCED TECHNOLOGY LLC (Mt. Laurel, N.J.).

"Methods for the design of nonallosteric sirtuin activating compounds" was invented by Raj Chakrabarti (Moorestown, N.J.), Xiangying Guan (Cherry Hill, N.J.) and Alok Upadhyay (Mount Laurel, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides workflows for the discovery of nonallosteric sirtuin activation compounds. Workflows enable drug discovery of novel sirtuin activating compounds with prescribed effects on the binding in pockets near the active site interacting with flexible protein degrees of freedom around the active ...