ALEXANDRIA, Va., July 14 -- United States Patent no. 12,678,440, issued on July 14, was assigned to CASE WESTERN RESERVE UNIVERSITY (Cleveland) and UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh).

"Compositions and methods for treating misfolded protein ocular disorders" was invented by Yuanyuan Chen (Pittsburgh) and Krzysztof Palczewski (Cleveland).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method of treating an inherited ocular disorder associated with or caused by a misfolded ocular protein in a subject in need thereof includes administering to the subject a compound that promotes clearance of misfolded ocular protein."

The patent was filed on Feb. 26, 2021, unde...