US Patent Issued to Case Western Reserve University, Invictus Therapeutics on May 12 for "Compositions containing rapid-acting insulin analogues" (Massachusetts, Ohio, Indiana Inventors)

ALEXANDRIA, Va., May 12 -- United States Patent no. 12,622,949, issued on May 12, was assigned to Case Western Reserve University (Cleveland) and Invictus Therapeutics (Warwick, R.I.).

"Compositions containing rapid-acting insulin analogues" was invented by Michael A. Weiss (Indianapolis), Mentor Mulaj (North Ridgeville, Ohio), Laurie A. Broadwater (Kent, Ohio), Thomas Hattier (Cleveland Heights, Ohio) and Richard Berenson (Waban, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A pharmaceutical composition comprises an effective amount of an insulin analogue comprising modified A-chain and B-chain polypeptides. The modified A chain comprises one or more substitutions relative to wild-type human insulin ...