ALEXANDRIA, Va., Aug. 18 -- United States Patent no. 12,709,739, issued on Aug. 18, was assigned to Cartesian Therapeutics Inc. (Frederick, Md.).
"Engineered cells secreting therapeutic enzymes" was invented by Yi Zhang (Gaithersburg, Md.), C. Andrew Stewart (Frederick, Md.), Shaji Daniel (Germantown, Md.), Metin Kurtoglu (Bethesda, Md.) and Murat V. Kalayoglu (Silver Spring, Md.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are mammalian cells comprising a first exogenous nucleic acid encoding a DNAse protein and a second exogenous nucleic acid encoding another DNAse protein, such as DNASE1 protein and DNASE1L3 protein, that have improved properties, including the ability to degrades extrac...