ALEXANDRIA, Va., July 15 -- United States Patent no. 12,662,488, issued on June 23, was assigned to C4 Therapeutics Inc. (Watertown, Mass.).

"Spirocyclic compounds" was invented by Christopher G. Nasveschuk (Stoneham, Mass.), Fabian Dey (Basel, Switzerland), Annick Goergler (Colmar, France), Roger Norcross (Basel, Switzerland) and Philipp Schmid (Basel, Switzerland).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides compounds and intermediates. The present invention also provides compounds which bind to the ubiquitously expressed E3 ligase protein cereblon (CRBN) and their use for the treatment of abnormal cellular proliferation. The present invention also provides compounds that ma...