US Patent Issued to Buck Institute for Research on Aging on Aug. 25 for "N-propargylglycine: a unique inhibitor of proline dehydrogenase with brain-enhancing mitohormesis properties capable of mitigating the pathogenesis of neurodegenerative disorders" (California Inventors)

ALEXANDRIA, Va., Aug. 25 -- United States Patent no. 12,714,686, issued on Aug. 25, was assigned to Buck Institute for Research on Aging (Novato, Calif.).

"N-propargylglycine: a unique inhibitor of proline dehydrogenase with brain-enhancing mitohormesis properties capable of mitigating the pathogenesis of neurodegenerative disorders" was invented by Gary K. Scott (Berkeley, Calif.), Christopher C. Benz (Petaluma, Calif.) and Lisa M. Ellerby (San Anselmo, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "In certain embodiments, methods of activating the mitochondrial unfolded protein response (UPRmt) and inducing mitohormesis in the brain and/or central nervous system of a mammal are provided where the me...