US Patent Issued to BRL Medicine (Shanghai) on Aug. 11 for "SGRNA guiding PD1 gene for cleavage to achieve efficient integration of exogenous sequences" (Chinese Inventors)

ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,703,861, issued on Aug. 11, was assigned to BRL Medicine (Shanghai) Co. Ltd. (Shanghai).

"SGRNA guiding PD1 gene for cleavage to achieve efficient integration of exogenous sequences" was invented by Jiqin Zhang (Shanghai), Jiaxuan Yang (Shanghai), Yue Tian (Shanghai), Bing Du (Shanghai), Dali Li (Shanghai), Mingyao Liu (Shanghai) and Zaixi Xi (Shanghai).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed is an sgRNA guiding a PD1 gene for cleavage to achieve the efficient integration of exogenous sequences. The method for gene editing a PD1 gene in cells includes the steps of introducing a nuclease and an sgRNA into cells, and gene-editing the PD1 g...