ALEXANDRIA, Va., Sept. 15 -- United States Patent no. 12,735,488, issued on Sept. 15, was assigned to Bristol-Myers Squibb Co. (Princeton, N.J.).
"Antibodies binding to vista at acidic pH" was invented by Lin Hui Su (Somerville, Mass.) and Sabrina Mueller (Mountain View, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present application relates to antibodies specifically binding to the V-domain immunoglobulin-containing suppressor of T-cell activation (VISTA) at acidic pH and their use in cancer treatment. In some embodiments, the antibodies bind specifically to human VISTA at acidic pH, but do not significantly bind to human VISTA at neutral or physiological pH."
The patent was filed on Sept. 18...