US Patent Issued to Bristol-Myers Squibb on May 12 for "Anti-ICOS agonist antibodies and uses thereof" (California, Washington Inventors)

ALEXANDRIA, Va., May 12 -- United States Patent no. 12,622,954, issued on May 12, was assigned to Bristol-Myers Squibb Co. (Princeton, N.J.).

"Anti-ICOS agonist antibodies and uses thereof" was invented by John J. Engelhardt (Fremont, Calif.), Mark J. Selby (San Francisco), Alan J. Korman (Piedmont, Calif.), Mary Diane Feingersh (Hayward, Calif.) and Brenda L. Stevens (Seattle).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides isolated monoclonal antibodies (e.g., humanized and human monoclonal antibodies) that bind to human Inducible T Cell COStimulator (ICOS) and exhibit therapeutically desirable functional properties, e.g., the ability to stimulate human ICOS activity. Nucleic a...