ALEXANDRIA, Va., March 17 -- United States Patent no. 12,580,049, issued on March 17, was assigned to BostonGene Corp. (Waltham, Mass.).

"Tumor microenvironment-based methods for assessing CAR-T and other immunotherapies" was invented by Nikita Kotlov (Limassol, Cyprus), Georgy Sagaradze (Moscow), Alexander Bagaev (Waltham, Mass.), Grigorii Nos (Moscow), Lev Begniagin (St. Petersburg, Russia), Dmitry Kravchenko (Yerevan, Armenia) and Anna Gribkova (Moscow).

According to the abstract* released by the U.S. Patent & Trademark Office: "Aspects of the disclosure relate to methods for determining whether or a subject is likely to respond to certain adoptive cell therapies (e.g., chimeric antigen receptor (CAR) T-cell therapy, etc.). In some emb...