ALEXANDRIA, Va., Aug. 5 -- United States Patent no. 12,698,486, issued on Aug. 4, was assigned to Boehringer Ingelheim International GmbH (Ingelheim am Rhein, Germany).
"Caspase-2 variants" was invented by Alois Jungbauer (Vienna), Nico Lingg (Vienna), Gerald Striedner (Vienna), Monika Cserjan-Puschmann (Langenzersdorf, Austria), Chris Oostenbrink (Vienna), Christoph Oehlknecht (Vienna), Christina Kroess (Innsbruck, Austria), Petra Engele (Innsbruck, Austria) and Rainer Schneider (Woergl, Austria).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention refers to a single-chain circular permuted caspase-2 comprising the following structure from N- to C-terminus: i) a small subunit of a caspase-2, or a fun...