US Patent Issued to BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM on Sept. 22 for "Methods for treating cancers with inhibitors targeting the role of GRB2 in DNA repair" (Texas Inventors)

ALEXANDRIA, Va., Sept. 24 -- United States Patent no. 12,742,209, issued on Sept. 22, was assigned to BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas).

"Methods for treating cancers with inhibitors targeting the role of GRB2 in DNA repair" was invented by John A. Tainer (Houston), Zamal Ahmed (Houston) and Zu Ye (Houston).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are methods for selecting and treating cancers that are homology-directed repair (HDR) proficient. As such, methods for sensitizing cancers to PARP inhibitor therapy and ionizing radiation are also provided. In some aspects, cancers are treated with a combination of a GRB2 inhibitor and a PARP inhibitor or a GRB2 ...