ALEXANDRIA, Va., March 31 -- United States Patent no. 12,590,054, issued on March 31, was assigned to Board of Regents, The University of Texas System (Austin, Texas).

"Use of D9-methadone for postoperative pain relief" was invented by Tatiana N. Nanovskaya (League City, Texas), Jun-Ho La (Galveston, Texas), Mahmoud S. Ahmed (Galveston, Texas) and Jigong Wang (League City, Texas).

According to the abstract* released by the U.S. Patent & Trademark Office: "Certain embodiments are directed to the use of d9-methadone as an alternative formulation for methadone, the d9-methadone having an improved absorption-distribution-metabolism-excretion profile, analgetic efficacy, and safety for the management of pain following injury such as trauma, di...