US Patent Issued to BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM on July 28 for "Pegylated kynureninase enzymes and uses thereof for the treatment of cancer" (Massachusetts, Texas Inventors)

ALEXANDRIA, Va., July 28 -- United States Patent no. 12,692,485, issued on July 28, was assigned to BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas).

"Pegylated kynureninase enzymes and uses thereof for the treatment of cancer" was invented by James Nolan (Boston), Michelle Zhang (Lexington, Mass.), George Georgiou (Austin, Texas), Everett Stone (Austin, Texas), John Blazeck (Austin, Texas) and Christos Karamitros (Austin, Texas).

According to the abstract* released by the U.S. Patent & Trademark Office: "Kynureninase enzymes covalently bound to polyethylene glycol are described. Aspects of the disclosure provide compositions and methods for improving the effective treatment of cancer by way of kynurenine depletion using s...