ALEXANDRIA, Va., July 14 -- United States Patent no. 12,680,089, issued on July 14, was assigned to BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas).

"Administration of kynurenine depleting enzymes for tumor therapy" was invented by George Georgiou (Austin, Texas) and Everett Stone (Austin, Texas).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods and compositions related to the use of a protein with kynureninase activity are described. For example, in certain aspects there may be disclosed a modified kynureninase capable of degrading kynurenine. Furthermore, certain aspects of the invention provide compositions and methods for the treatment of cancer with kynurenine depletion using the di...