ALEXANDRIA, Va., March 31 -- United States Patent no. 12,590,335, issued on March 31, was assigned to Board of Regents, The University of Texas System (Austin, Texas) and Yale University (New Haven, Conn.).
"Targeted measure of transcriptional activity related to hormone receptors" was invented by William Fraser Symmans (Houston), Bruno Sinn (Berlin), Christos Hatzis (Guilford, Conn.), Chunxiao Fu (Pearland, Texas) and Rosanna Lau (Houston).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are methods of determining tumoral sensitivity to hormonal (endocrine) therapy based upon an index of estrogen receptor (ER)- and progesterone receptor (PR)-related genes, referred to as the sensitivity to endo...