US Patent Issued to BioNTech on June 2 for "IL2 agonists" (German Inventors)

ALEXANDRIA, Va., June 2 -- United States Patent no. 12,643,930, issued on June 2, was assigned to BioNTech SE (Mainz, Germany).

"IL2 agonists" was invented by Ugur Sahin (Mainz, Germany), Sina Fellermeier-Kopf (Mainz, Germany), Alexander Muik (Mainz, Germany), Mathias Vormehr (Mainz, Germany) and Lena Mareen Kranz (Mainz, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to variants of interleukin-2 (IL2). In particular, the invention relates to a polypeptide comprising a mutein of human IL2 or of a functional variant of human IL2, wherein the human IL2 or functional variant thereof is substituted such that affinity for the BetaGamma IL2 receptor complex (IL2RBetaGamma) is enhanced...