US Patent Issued to BIOND BIOLOGICS on March 31 for "Shedding blocking agents with increased stability" (Israeli Inventors)

ALEXANDRIA, Va., March 31 -- United States Patent no. 12,589,163, issued on March 31, was assigned to BIOND BIOLOGICS LTD. (Misgav, Israel).

"Shedding blocking agents with increased stability" was invented by Motti Hakim (Kibbutz Gazit, Israel), Anna Fridman-Dror (Kibbutz Dalia, Israel), Ilana Mandel (Manof, Israel), Tehila Ben-Moshe (Tel Aviv, Israel), Yair Sapir (Manof, Israel), Avidor Shulman (Rakefet, Israel), Lilach Chen Zeltsburg (Nahariya, Israel) and Ayala Lewkowicz (Kibbutz Kfar Szold, Israel).

According to the abstract* released by the U.S. Patent & Trademark Office: "Agents comprising at least two moieties separated by a linker, wherein a first moiety binds mCD28 on a surface of a cell and inhibits proteolytic cleavage of the m...