US Patent Issued to Biohaven Therapeutics on July 21 for "Bifunctional degraders for the treatment of Graves' disease" (Connecticut, New York, Massachusetts Inventors)

ALEXANDRIA, Va., July 21 -- United States Patent no. 12,685,782, issued on July 21, was assigned to Biohaven Therapeutics Ltd. (Tortola, British Virgin Islands).

"Bifunctional degraders for the treatment of Graves' disease" was invented by Anna Bunin (Queens, N.Y.), Seong Lee (West Haven, Conn.), Kathren Croce (New Haven, Conn.), Miranda L. Simes (Somerville, Mass.), Edward Deramon (Hamden, Conn.) and Mariano Oppikofer (Stamford, Conn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A composition of matter including an anti-TSH receptor autoantibody-binding moiety, a cellular receptor-binding moiety that binds to hepatocytes or other degrading cells through asialoglycoprotein receptors (ASGPR) on the surface ...