ALEXANDRIA, Va., July 28 -- United States Patent no. 12,692,495, issued on July 28, was assigned to BIOGEN MA INC. (Cambridge, Mass.).
"Methods of preparing oligonucleotide compositions using ultrafiltration/diafiltration" was invented by Robert S. Gronke (Cambridge, Mass.), Jonas P. Immel-Brown (Cambridge, Mass.) and Geetha Govindan (Cambridge, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are methods for preparing compositions containing oligonucleotides. Methods of this disclosure involve subjecting an aqueous solution of a oligonucleotide to ultrafiltration/diafiltration (UF/DF) in order to form a retentate containing the oligonucleotide, where the ultrafiltration/diafiltration (U...