US Patent Issued to Beth Israel Deaconess Medical Center on Nov. 3 for "Compositions and methods for decreasing inflammation" (Massachusetts Inventors)

ALEXANDRIA, Va., Nov. 3 -- United States Patent no. 12,781,205, issued on Nov. 3, was assigned to Beth Israel Deaconess Medical Center Inc. (Boston).

"Compositions and methods for decreasing inflammation" was invented by Simon C. Robson (Boston) and Elizabeth H. Zhong (Boston).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention features bifunctional, soluble ecto-enzymes that are engineered to hydrolyze extracellular nucleotide triphosphates (e.g., ATP) to a nucleoside (e.g., adenosine), through the fusion of the ectodomains (ECD) of an ecto-nucleoside triphosphate diphosphohydrolase (E-NTPDase) and a nucleotide monophosphatase (NMPAse), such as an ecto-5' nucleotidase (eN), alkaline phosphat...