US Patent Issued to BEIJING JUNKE HUAYUAN MED TECH on March 31 for "Substituted entecavir monophosphate alaninamide phenolic esters for resisting hepatitis b virus" (Chinese Inventors)

ALEXANDRIA, Va., March 31 -- United States Patent no. 12,590,097, issued on March 31, was assigned to BEIJING JUNKE HUAYUAN MED TECH Co. LTD. (Beijing).

"Substituted entecavir monophosphate alaninamide phenolic esters for resisting hepatitis b virus" was invented by Bohua Zhong (Beijing), Hongwu Li (Beijing) and Xiaozai Wang (Beijing).

According to the abstract* released by the U.S. Patent & Trademark Office: "An entecavir monophosphate alaninamide phenolic ester derivative is represented by formula II. It has non-toxic pharmaceutically acceptable salts. In formula II, X is H, halogen, R or -OR, and R is a C1-3 alkyl or a substituted C1-3 alkyl. The entecavir monophosphate alaninamide phenolic ester derivative or the non-toxic pharmaceuti...