ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,746,273, issued on Sept. 29, was assigned to Baylor College of Medicine (Houston).
"CD5 chimeric antigen receptor for adoptive T cell therapy" was invented by Maksim Mamonkin (Houston) and Malcolm K. Brenner (Houston).
According to the abstract* released by the U.S. Patent & Trademark Office: "Embodiments of the disclosure include methods and compositions related to immunotherapy that targets CD5. In particular embodiments, immune cells engineered to comprise a chimeric antigen receptor (CAR) that targets CD5 are contemplated, and uses thereof. In particular embodiments, the immune cells expressing the CAR do not commit fratricide to any great extent against T cells that express CD5...