US Patent Issued to Bayer on July 14 for "Enantioselective hydrogenation of 4-substituted 1,2-dihydroquinolines in presence of a chiral iridium catalyst and an additive" (German, Chinese Inventors)

ALEXANDRIA, Va., July 14 -- United States Patent no. 12,679,808, issued on July 14, was assigned to Bayer AG (Leverkusen, Germany).

"Enantioselective hydrogenation of 4-substituted 1,2-dihydroquinolines in presence of a chiral iridium catalyst and an additive" was invented by Christoph Schotes (Duesseldorf, Germany), Matthias Beller (Nienhagen, Germany), Kathrin Junge (Rostock, Germany), Weiping Liu (Shanghai), Jacob Schneekoenig (Leipzig, Germany) and Thomas Leischner (Rostock, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to a process for preparing optically active 4-substituted 1,2,3,4-tetrahydroquinolines comprising enantioselective hydrogenation of the corresponding 4-subs...