ALEXANDRIA, Va., Aug. 18 -- United States Patent no. 12,709,754, issued on Aug. 18, was assigned to Band Therapeutics LLC (Belmont, Mass.).
"Regulation of von Willebrand factor (VWF)" was invented by Shuhao Zhu (Concord, Mass.) and James C. Gilbert (Bethlehem, Conn.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to agents, compositions targeting to von Willebrand factor (VWF). The VWF targeting agents are synthetic polynucleotides, including VWF binding agents and their reversal agents. The VWF binding agents are VWF binding aptamers that bind to and inhibit the VWF activities. The VWF binding agents can be reversed using reversal agents to reverse the inhibitory effect and the...