US Patent Issued to AUGUSTA UNIVERSITY RESEARCH INSTITUTE on June 23 for "Substituted pyrazolo[4,3-Dpyrimidines as gut-targeted phosphodiesterase inhibitors" (Georgia Inventors)

ALEXANDRIA, Va., July 15 -- United States Patent no. 12,662,485, issued on June 23, was assigned to AUGUSTA UNIVERSITY RESEARCH INSTITUTE INC. (Augusta, Ga.).

"Substituted pyrazolo[4,3-Dpyrimidines as gut-targeted phosphodiesterase inhibitors" was invented by Darren Browning (Evans, Ga.) and Iryna Lebedyeva (Augusta, Ga.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are compounds that inhibit phosphodiesterase 5 (PDE5) and methods of use thereof. In some forms, the compounds can have a structure according to Formula I:Also provided are pharmaceutical compositions and medicaments that include the compounds described herein as well as methods of treating gastrointestinal diseases and disorders...