ALEXANDRIA, Va., July 14 -- United States Patent no. 12,678,498, issued on July 14, was assigned to ASTEX THERAPEUTICS LTD (Cambridge, Great Britain).

"FGFR/PD-1 combination therapy for the treatment of cancer" was invented by Jayaprakash Karkera (Germantown, Md.), Suso Jesus Platero (Washington Crossing, Pa.), Raluca Verona (Swarthmore, Pa.) and Matthew V. Lorenzi (Philadelphia).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are combination therapies for the treatment of cancer. In particular, the disclosed methods are directed to treatment of cancer in a patient comprising administering an antibody that blocks the interaction between PD-1 and PD-L1 and an FGFR inhibitor, wherein the antibody...