US Patent Issued to ASAHI KASEI PHARMA, VERNALIS (R&D) on March 31 for "Pyrimidine-and nitrogen-containing bicyclic compound" (British, Japanese Inventors)

ALEXANDRIA, Va., March 31 -- United States Patent no. 12,590,090, issued on March 31, was assigned to ASAHI KASEI PHARMA Corp. (Tokyo) and VERNALIS (R&D) Ltd. (Cambridge, Great Britain).

"Pyrimidine-and nitrogen-containing bicyclic compound" was invented by Koichiro Arai (Tokyo), Kenichiro Takaba (Tokyo), Masakazu Atobe (Tokyo), Misato Takashima (Tokyo), Naomi Aono (Tokyo), Andrew John Potter (Cambridge, Great Britain) and Daniel Paul Maddox (Cambridge, Great Britain).

According to the abstract* released by the U.S. Patent & Trademark Office: "A compound represented by the general formula (1) or a salt thereof, which has a superior IRAK-4 inhibitory activity, and is useful as active ingredients of medicaments for prophylactic treatment an...