US Patent Issued to Arvinas Operations on Feb. 24 for "Indazole based compounds and associated methods of use" (Connecticut, New Jersey Inventors)

ALEXANDRIA, Va., Feb. 24 -- United States Patent no. 12,559,506, issued on Feb. 24, was assigned to Arvinas Operations Inc. (New Haven, Conn.).

"Indazole based compounds and associated methods of use" was invented by Erika Marina Vieira Araujo (Woodbridge, Conn.), Michael Berlin (Flemington, N.J.), Hanqing Dong (Madison, Conn.), Steven M. Sparks (Guilford, Conn.), Jing Wang (Milford, Conn.) and Wei Zhang (Madison, Conn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Bifunctional compounds, which find utility as modulators of leucine-rich repeat kinase 2 (LRRK2), are described herein. In particular, the hetero-bifunctional compounds of the present disclosure contain on one end a moiety that binds to the cereb...