ALEXANDRIA, Va., May 26 -- United States Patent no. 12,637,492, issued on May 26, was assigned to Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Ariz.).
"Peptide inhibitors of focal adhesion kinase activity and uses thereof" was invented by Timothy Marlowe (Phoenix) and Warren S. Weiner (Phoenix).
According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure provides peptides which have an affinity for the focal adhesion targeting (FAT) domain of focal adhesion kinase (FAK). In particular, the peptides are modified and derived from the sequence of the LD2 alpha helical domain of paxillin (e.g., LD2 peptides), the LD4 domain of paxillin (e.g., LD4 peptides), and CD8 peptides. These pe...