ALEXANDRIA, Va., March 17 -- United States Patent no. 12,577,289, issued on March 17, was assigned to ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Ariz.).
"Surrogate co-receptors for t cells and methods of use" was invented by Michael S. Kuhns (Tucson, Ariz.), Deepta Bhattacharya (Tucson, Ariz.) and Heather Lynn Bronnimann (Tucson, Ariz.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Surrogate co-receptors for T cells, including T cells expressing chimeric receptors comprising major histocompatibility molecules grafted onto T cell receptor molecules. The surrogate co-receptors feature a portion of CD8, wherein the Ig domains of CD8 are replaced with Ig domains that confer novel sp...