ALEXANDRIA, Va., Sept. 1 -- United States Patent no. 12,725,282, issued on Sept. 1, was assigned to Arizona Board of Regents on Behalf of Arizona State University (Tempe, Ariz.).

"Systems and methods for simultaneous single particle tracking, phase retrieval and PSF reconstruction" was invented by Steve Presse (Scottsdale, Ariz.), Mohamadreza Fazel (Tempe, Ariz.) and Zeliha Kilic (Memphis, Tenn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "3D particle tracking and localization provide direct means to monitor details within nano-scale environments. However, a major shortcoming of 3D techniques is the sample induced aberrations due to inhomogeneous refractive index, resulting in distortion of point spread fu...