ALEXANDRIA, Va., July 28 -- United States Patent no. 12,691,151, issued on July 28, was assigned to Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Ariz.).
"Methods and compositions for improving oncolytic virus infection for nonpermissive cancers" was invented by Douglas Grant McFadden (Tempe, Ariz.) and Mohammed Masmudur Rahman (Chandler, Ariz.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are methods and compositions of treating cancer, comprising administrating to a subject with cancer a therapeutically effective amount of an oncolytic virus and a nucleocytoplasmic transport inhibitor. Further described herein are methods of converting a nonpermissive cancer ...