US Patent Issued to ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY on July 28 for "Genetically engineered human fetal liver niche as platform for biomanufacturing of hematopoietic stem cells" (Arizona, Pennsylvania Inventors)

ALEXANDRIA, Va., July 28 -- United States Patent no. 12,692,479, issued on July 28, was assigned to ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Ariz.).

"Genetically engineered human fetal liver niche as platform for biomanufacturing of hematopoietic stem cells" was invented by Mo Reza Ebrahimkhani (Scottsdale, Ariz.), Jeremy Velazquez (Pittsburgh), Samira Kiani (Scottsdale, Ariz.) and Ryan Patrick LeGraw (Pittsburgh).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to methods for expanding populations of hematopoietic stem cells (HSCs) using a genetically engineered human fetal liver niche and compositions of purified ex vivo expanded HSCs. Also pro...