ALEXANDRIA, Va., July 21 -- United States Patent no. 12,686,724, issued on July 21, was assigned to Aprilbio Co. Ltd (Chuncheon-si, South Korea).

"Monoclonal antibodies and antigen binding fragments thereof for suppressing CD73 immune checkpoint and uses thereof" was invented by Sang Hoon Cha (Chuncheon-si, South Korea).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are monoclonal antibodies and antigen binding fragments thereof for suppressing a CD73 immune checkpoint, and uses thereof, wherein the antibodies or antigen binding fragments thereof can bind to CD73, reduce enzymatic activity of CD73 protein, and inhibit cancer metastasis or cancer growth, thus enabling uses thereof as therapeutic agent...