ALEXANDRIA, Va., April 15 -- United States Patent no. 12,600,708, issued on April 14, was assigned to Apoapsis Holdings LLC (Longmont, Colo.).

"Prodrug compounds of 3,4-methylenedioxymethamphetamine (MDMA) and methods of synthesizing the same" was invented by Denton W. Hoyer (West Haven, Conn.), Robert F. Roscow (Longmont, Colo.), Rong Ling (Edmonton, Canada) and Chuanjun Gao (Edmonton, Canada).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention includes a novel class of MDMA carbamates that can be activated in vivo as prodrugs. The MDMA prodrugs of the invention are enzymatically cleaved in vivo and produce alcohols of low toxicity that are well tolerated and metabolized in humans."

The pat...