ALEXANDRIA, Va., Feb. 24 -- United States Patent no. 12,559,724, issued on Feb. 24, was assigned to apceth GmbH & Co. KG (Munich).
"Genetically modified mesenchymal stem cell expressing Klotho" was invented by Christine Gunther (Munich), Manfred Stangl (Sauerlach, Germany) and Felix Hermann (Munich).
According to the abstract* released by the U.S. Patent & Trademark Office: "A genetically modified mesenchymal stem cell including an exogenous nucleic acid including a Klotho encoding region operably linked to a promoter or promoter/enhancer combination, wherein the genetically modified mesenchymal stem cell exhibits increased Klotho expression compared to an unmodified mesenchymal stem cell. Also disclosed are methods of treating a patient ...