US Patent Issued to Animatus Biosciences on July 28 for "Cardiac cell proliferation by administering inhibitors of SAV1, NF2, MOB1 and/or mutant SRF" (Texas Inventors)

ALEXANDRIA, Va., July 28 -- United States Patent no. 12,692,497, issued on July 28, was assigned to Animatus Biosciences Inc. (Houston).

"Cardiac cell proliferation by administering inhibitors of SAV1, NF2, MOB1 and/or mutant SRF" was invented by Robert Joel Schwartz (Houston) and Nada Bejar (Pearland, Texas).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are DsiRNA inhibitors for the genes encoding SAV1, NF2 and MOB1, which cause proliferation of cardiomyocytes on administration to a mammal. The DsiRNA inhibitors can also be administered with a mutant SRF (153-A3) or an mRNA encoding it, and/or Yap5SA (a Yap mutant) or an encoding mRNA, which enhance the proliferative effect on cardiomyocytes. Muta...