US Patent Issued to Amyris on Sept. 15 for "Amorpha-4,11-diene 12-monooxygenase variants and uses thereof" (California Inventors)

ALEXANDRIA, Va., Sept. 15 -- United States Patent no. 12,735,683, issued on Sept. 15, was assigned to Amyris Inc. (Emeryville, Calif.).

"Amorpha-4,11-diene 12-monooxygenase variants and uses thereof" was invented by Christopher J. Paddon (Emeryville, Calif.), Hanxiao Jiang (Emeryville, Calif.) and Stephanie H. Kung (Emeryville, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are genetically modified host cells, compositions, and methods for improved production of artemisinic acid. The host cells are genetically modified to contain a heterologous nucleic acid that expresses novel and optimized variants of Amorpha-4,11-diene 12-monooxygenase. Also provided herein are methods for screening...