ALEXANDRIA, Va., Sept. 15 -- United States Patent no. 12,735,484, issued on Sept. 15, was assigned to AMGEN RESEARCH (MUNICH) GMBH (Munich).

"Bispecific single chain antibodies with specificity for high molecular weight target antigens" was invented by Peter Kufer (Munich), Claudia Blumel (Munich) and Roman Kischel (Munich).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a method for the selection of bispecific single chain antibodies comprising a first binding domain capable of binding to an epitope of CD3 and a second binding domain capable of binding to the extracellular domain cell surface antigens with a high molecular weight extracellular domain. Moreover, the invention pro...