US Patent Issued to Amber Bio on July 21 for "Methods and compositions for trans-splicing utilizing trifunctional elements" (California Inventors)

ALEXANDRIA, Va., July 21 -- United States Patent no. 12,686,869, issued on July 21, was assigned to Amber Bio Inc. (South San Francisco, Calif.).

"Methods and compositions for trans-splicing utilizing trifunctional elements" was invented by Jacob Borrajo (San Francisco), Brigit Riley (San Francisco), Kamyab Javanmardi (San Francisco), Patricia Biezonski (San Francisco) and Samuel Demario (San Francisco).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides a trans-splicing molecule that has a trifunctional element suitable for targeted trans-splicing of an RNA or pre-mRNA molecule."

The patent was filed on Jan. 23, 2026, under Application No. 19/457,807.

*For further information, in...